Synthesis of 2-Aryl-2-Oxazolines from β-hydroxy Amides using PPh3/Tf2O System

 
             
   
   

DOI: 10.22607/IJACS.2025.1301001

   

Research Article

     

 

   
H. Keerthi, Vommina Venkata Sureshbabu*

ABSTRACT

 

A one- pot, mild, and rapid synthesis of 2-aryl-2-oxazolines starting from β-hydroxy amides using triphenylphosphine/triflic anhydride system has been described. Various 2-aryl-2-oxazolines were synthesized utilizing this new protocol. All the products were obtained in good yields.
 

 

 

 

     

Key words:  2-aryl-2-oxazolines, triflic anhydride, triphenylphosphine, β-hydroxy amides.

 

 

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Indian Journal of Advances in Chemical Science,

Volume: 13, Issue : 1,  January 2025

ISSN No.: 2320-0898 (Print); 2320-0928 (Electronic)

   
     
                 
     
                 
                 
                 
               
 

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