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We fabricated Co0.21Cu0.79O
nanoparticles from co-precipitation followed by thermal
decomposition of cobalt doped copper creatinate hydrazinate
([Co0.21Cu0.79(Cre)2(N2H4)2]) inorganic precursor. The inorganic
precursor was characterized through energy dispersive X-ray
spectroscopy (EDS), Inductively Coupled Plasma Atomic Emission
Spectrophotometry (ICP AES), Fourier transform infrared (FT-IR), and
thermogravimetry-differential thermal analyser analysis. To
characterize the composition, structural phase, chemical state,
morphological, and textural properties of fabricated Co0.21Cu0.79O
nanoparticles techniques such as EDS, ICP-AES, X-ray diffraction,
FT-IR, Raman, X-ray photoelectron spectroscopy, Scanning electron
microscopy, transmission electron microscope, and Brunauer–Emmett–Teller
were used. The in vitro antioxidant activity of Co0.21Cu0.79O
nanoparticles was assessed by 2,2-diphenyl-1-picryl-hydrazyl-hydrate
free radical assay. Furthermore, the in vitro cytotoxic activity of
Co0.21Cu0.79O nanoparticles was evaluated against human embryonic
kidney 293 and HeLa cell lines using
3-[4,5-dimethylthiazol-2-yl]2,5-diphenyltetrazolium bromide assay. |
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Key words: Nanoparticles, Creatinate,
Co-precipitation, Thermal decomposition, Characterization, In vitro
antioxidant, In vitro cytotoxicity. |
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