Abstract

A new series of compounds of (2-Benzothiazolyl-2’)hydrazono-3-phenyl-5-arylidene-4-thiazolidinone derivatives and 2-phenyl-
(3-benzothiazolyl-2’)hydrazono-5-arylidene-4-thiazolidinone derivative 4(a-i) are prepared from 2-hydrazinobenzothiazole
taking as a starting material. The inclusion complexes of respective compounds can be prepared with β-cyclodextrins using
the co-precipitation method. These synthesized compounds and their inclusions have been characterized with their spectral,
analytical data and screened for their antibacterial activities. With the formation of inclusion complexes, the compounds show
more biological activeness as compared to the parent compounds. Finally, the antibacterial study proves that the inclusion
complexes of 4d show greater efficiency towards Staphylococcus aureus whereas 4e shows greater efficiency against Escherichia
coli bacteria’s respectively.