Synthesis, Characterization and Biological Evaluation of 1,3-Bis(5- Hydantoinyloxy) Benzenes
Ramesh G. Surose*, V. N. Ingle, L. J. Paliwal
DOI: 10.22607/IJACS.2021.903010
Volume 9, Issue 3 | Pages: 162-165
Abstract
An efficient and straightforward two-step approach toward 1,3-bis(5-hydantoinyloxy)benzenes was developed. A hydantoin
is reacted with bromine to produce 5-bromohydantoin, which on reaction with the resorcinol’s to produce corresponding
1,3-bis(5-hydantoinyloxy)benzenes in the presence of K2CO3 in dioxane. The structures of newly synthesized compounds
have been reputable on the basis of their spectral data. Their biological activities against Gram +ve and Gram −ve bacteria are
reported.
Keywords
Hydantoin Bis-hydantoin Anticonvulsant Resorcinol.References
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Citation
Ramesh G. Surose*, V. N. Ingle, L. J. Paliwal. Synthesis, Characterization and Biological Evaluation of 1,3-Bis(5- Hydantoinyloxy) Benzenes. J Appl Pharm Sci. 2021; 9(3):162-165.