On the Mechanism of Uric Acid Oxidation with Lead Dioxide and with Alkaline Hydrogen Peroxide

F. Sánchez-Viesca*, R. Gómez

DOI: 10.22607/IJACS.2020.803001

Volume 8, Issue 3 | Pages: 78-80

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Abstract

The metabolic pathways of uric acid have been studied in biological chemistry (enzymatic reactions). However, the course of
some reported chemical reactions is unknown. In this communication, we provide the route of two independent oxidations of
uric acid, with different reagents and reaction media. The electron flow is given, step by step, until the final product: allantoin.
The intermediate reactions are fully commented.

Keywords
Allantoin Epoxidation Nitrene Push-pull effects Ring closure and opening.
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Citation

F. Sánchez-Viesca*, R. Gómez. On the Mechanism of Uric Acid Oxidation with Lead Dioxide and with Alkaline Hydrogen Peroxide. J Appl Pharm Sci. 2020; 8(3):78-80 .