Synthesis, Crystal Structure Refinement, and Morphological Study of Bioactive Material: Strontium and Iron-Substituted Nano-Hydroxyapatite: Ca10-xMx(PO4)6(OH)2 (M=Sr and Fe and 0 ≤ x ≤ 0.1)
O. P. Shrivastava*, Ramesh C. Deka, Rashmi Chourasia, Rasnadevi
DOI: 10.22607/IJACS.2019.701001
Volume 7, Issue 1 | Pages: 1-11
Abstract
Nano-hydroxyapatite (HA) is a bioactive and important material well known for several applications. Rietveld refinement and
structural analysis of X-ray powder diffraction patterns have been investigated to understand the effect of Sr and Fe substitution
on the structural properties of bioactive material Ca10-xMx(PO4)6(OH)2 or Ca5−xMx(PO4)3(OH) where M=Sr and Fe and x=0.05).
The crystal chemistry of Sr- and Fe-substituted HA phases has been investigated using General Structure Analysis System
programming. Sr- and Fe-substituted HA phases crystallize in the space group P 63/m; Z=2. Powder diffraction data have been
subjected to Rietveld refinement to arrive at a satisfactory structural convergence of R-factors. The expected overall decrease
of the lattice constants in the samples is explained in terms of local lattice distortions. The unit cell volume and polyhedral
distortion increase with a rise in the size of loaded cation in the HA matrix. Scanning electron microscopy, transmission electron
microscopy, and energy-dispersive X-ray analysis provide evidence of Sr and Fe in the HA matrix.
Keywords
Bioactive nanomaterial Hydroxyapatite X-ray diffraction General structure analysis system Structure refinement Fourier transform infrared Scanning and transmission electron microscopy.References
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Citation
O. P. Shrivastava*, Ramesh C. Deka, Rashmi Chourasia, Rasnadevi. Synthesis, Crystal Structure Refinement, and Morphological Study of Bioactive Material: Strontium and Iron-Substituted Nano-Hydroxyapatite: Ca10-xMx(PO4)6(OH)2 (M=Sr and Fe and 0 ≤ x ≤ 0.1). J Appl Pharm Sci. 2019; 7(1):1-11.