Synthesis of 2-Aryl-2-Oxazolines from β-hydroxy Amides using PPh3/Tf2O System

H. Keerthi, Vommina Venkata Sureshbabu*

DOI: 10.22607/IJACS.2025.1301001

Volume 13, Issue 1 | Pages: 1-9

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Abstract

A one- pot, mild, and rapid synthesis of 2-aryl-2-oxazolines starting from β-hydroxy amides using triphenylphosphine/triflic anhydride system has been described. Various 2-aryl-2-oxazolines were synthesized utilizing this new protocol. All the products were obtained in good yields.

Keywords
2-aryl-2-oxazolines triflic anhydride triphenylphosphine β-hydroxy amides.
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Citation

H. Keerthi, Vommina Venkata Sureshbabu*. Synthesis of 2-Aryl-2-Oxazolines from β-hydroxy Amides using PPh3/Tf2O System. J Appl Pharm Sci. 2025; 13(1):1-9.