Abstract

Trace elements are naturally occurring inorganic substance required in humans in amounts <100 mg/day. They
are essential components of biological structures and have an important effect on and play a key role in a variety
of the processes necessary for life throughout mediate vital biochemical reactions. Excessive levels, a level higher
than needed for biological functions, of these elements can be toxic for the body health. Therefore, it has been
found that the imbalances in the optimum levels of trace elements may adversely affect biological processes
and are associated with many fatal diseases, such as cancers. Recently, efforts have been focused to attempt to
advance understand of the relationship between heavy metal, trace elements, and their role in cancers. Many
studies indicated the remarkable of specific elements that may be of value and may have prognostic significance
in the early diagnosis, prognosis, and therapy evaluation of some diseases, especially various types of cancer.