DNA Binding and Biological Activities of Ternary Copper(II) Complexes Containing L-valine and Urea
P. C. Saravanan, M. Murali Krishnan, M. N. Arumugham*
DOI: 10.22607/IJACS.2017.504014
Volume 5, Issue 4 | Pages: 324-329
Abstract
Ternary copper complexes [Cu(phen)(L-val)U)] 1 and [Cu(bpy)(L-val)U)] 2 (phen - 1,10-phenanthroline
bpy - 2,2’-bipyridyl, L-val - L-valine and U - Urea), have been synthesized and characterized by CHN analysis,
electronic absorption, infrared, and electron paramagnetic resonance spectral studies. They have been tested for
their in vitro DNA binding activities by the spectroscopic methods such as ultraviolet-visible spectral studies,
emission spectral studies, viscosity, and cyclic voltammetry measurement. The antibacterial and antifungal
studies suggested that complexes possess potential biological activities.
Keywords
L-valine Heterocyclic bases Cu(II) complex DNA binding.References
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Citation
P. C. Saravanan, M. Murali Krishnan, M. N. Arumugham*. DNA Binding and Biological Activities of Ternary Copper(II) Complexes Containing L-valine and Urea. J Appl Pharm Sci. 2018; 5(4):324-329.