Vilsmeier-Haack Methodology as a Key Step to Novel Heterocycles: Synthesis of 3-phenyl-1-(3-phenylquinolin-2-yl)-1H-pyrazole-4-carbaldehyde

Manisekar Sathiyaseelan, Amaladoss Nepolraj, Pandian Pitchai*, Gengan Robert Moonsamy

DOI:

Volume 4, Issue 2 | Pages: 172-179

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Abstract

The synthesis of 3-phenyl-1-(3-phenylquinolin-2-yl)-1H-pyrazole-4-carbaldehyde is achieved through a dual
utility of Vilsmeier-Haack reaction. The utility of cheaper precursors in addition to easy work-up procedures
contributes to an important synthetic strategy.

Keywords
Vilsmeier Haack 3-phenyl-1-(3-phenylquinolin-2-yl)-1H-pyrazole-4-carbaldehyde 2-chloro-3- phenylquinoline.
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Citation

Manisekar Sathiyaseelan, Amaladoss Nepolraj, Pandian Pitchai*, Gengan Robert Moonsamy. Vilsmeier-Haack Methodology as a Key Step to Novel Heterocycles: Synthesis of 3-phenyl-1-(3-phenylquinolin-2-yl)-1H-pyrazole-4-carbaldehyde. J Appl Pharm Sci. 2016; 4(2):172-179.