Abstract

Cataract is referred as opacity of lens due to multi factorial etiology. All the constituents of the protecting
glutathione system including glutathione redox cycle and its enzymes, glutathione reductase, glutathione-s-
transterase, g- glutamyl transpetidase were studied the mean value of GR activity is decreases under
cataractous condition by 50.1%. Similarly, the GST activity and the GTP activity is also decrease under
cataractous condition. It appears that the glutathione reductase system could still be functioning in the
cataractous lens. The absence of oxidized glutathione in cataractous lenses would support this conclusion.