Microwave Induced Solvent-free and Catalyst-free Synthesis of 1,4- Dihydropyridine Derivatives using Ammonium Bicarbonate
B. Vijayakumar
DOI:
Volume 1, Issue 2 | Pages: 77-83
Abstract
One-pot synthesis of 1,4-dihydropyridine derivatives by reacting an aldehyde, a β-ketoester and ammonium
bicarbonate in the presence of microwaves without a catalyst under solvent-free conditions is described. Using
this green method, 1,4-dihydropyridine derivatives can be obtained in good yields in short reaction times.
Keywords
Hantzsch reaction dihydropyridines ammonium bicarbonate microwave solvent-freeReferences
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Citation
B. Vijayakumar. Microwave Induced Solvent-free and Catalyst-free Synthesis of 1,4- Dihydropyridine Derivatives using Ammonium Bicarbonate. J Appl Pharm Sci. 2013; 1(2):77-83.