Abstract

A series of diorganotin(IV) complexes of N-(2-hydroxy-1-naphthylidene) glycine (1), having general formula
[Me2SnOPri(Hhngl)] (2), [Me2Sn(Hhngl)2] (3), [Bu2SnOPri(Hhngl)] (4), [Bu2Sn(Hhngl)2] (5), [Ph2Sn(hngl)]
(6), [Ph2Sn(Hhngl)2] (7), [where H2hngl = N-(2-hydroxy-1-naphthylidene) glycine] were synthesized by
reacting of diorganotin(IV)chloride with the ligand, with the aid of sodium iso-propoxide in appropriate
stiochiometric ratios (1:1, 1:2). All the complexes exhibit good antibacterial activity against two Gram-positive
bacteria namely, Staphylococcus aureus, Bacillus subtilis and two Gram-negative bacteria namely, Escherichia
coli and Pseudomonas aeruginosa. All the complexes were also exhibit remarkable antifungal activity against
three pathogenic fungi namely, Aspergillus niger, A. flavus and Penicillium sp.